Description
| Specification line | Entry |
|---|---|
| Structural class | Dipeptide ester: a phenylacetyl group on proline, coupled to glycine, esterified with ethanol |
| Empirical formula | C17H22N2O4 |
| Formula mass | 318.37 g/mol |
| Registry number | 157115-85-0 |
| Alternative name | Omberacetam |
| Stereochemistry | A single stereocentre, inherited from L-proline |
| Functional groups | Two amide linkages and one ethyl ester |
| Storage regime | Dry, dark, refrigerated, with freezer conditions for long holding, as stated by the supplier |
The table above describes a peptide-derived ester rather than a typical heterocyclic solid, and that distinction drives every handling decision that follows.
Three linkages, three failure modes
The molecule contains one ethyl ester and two amide bonds, and they do not age at the same rate. The ester is the vulnerable member: moisture in a basic environment cleaves it to the corresponding acid and ethanol, and that acid is considerably more polar than the parent, surfacing early in a reversed-phase run. The amide linkages are far more durable and survive conditions the ester does not.
This asymmetry supplies a simple stability test. A chromatogram showing one new polar peak that grows with storage time usually points at the ester rather than at wholesale decomposition, and a batch caught at that stage still has a defensible identity even if its assay has drifted downward. Zobacz również odczynnik w opakowaniu gramowym: PRL-8-53, 1000mg czystej substancji ≥ 99%..
The stereocentre inherited from proline
The proline residue carries the only stereocentre, and its configuration is part of the substance identity, not a footnote to it. Prolonged contact with strong base is the classical route to epimerisation at a carbon next to a carbonyl, which is one more reason to keep the material away from alkaline detergent residues on glassware. Plain reversed-phase chromatography cannot separate the two configurations; a chiral stationary phase or an optical rotation measurement can.
Practical control points
- Bring a refrigerated vial to ambient temperature before breaking the seal.
- Weigh briskly under dry air, since the solid takes up atmospheric water.
- Use clean, neutral glassware — traces of alkaline detergent are enough to start ester cleavage in a stock solution.
- Record water content beside the assay, because a damp batch understates its own purity by mass.
- Re-qualify any container that has been opened repeatedly across several months.
What an acceptable certificate says
A usable certificate names the analytical method behind each number, states water content and residual solvents from the synthesis, and carries the batch identifier printed on the vial. Where the method is absent, the assay figure describes the supplier’s confidence rather than the material itself, and every later calculation leaning on it carries that uncertainty forward unchanged. Zobacz również materiał badawczy o zbliżonej specyfikacji: Modafinil (CAS 68693-11-8) — wzór sumaryczny C15H1.
Materiały o zbliżonej charakterystyce
- Modafinil (CAS 68693-11-8) — wzór sumaryczny C15H15NO2S, masa molowa i
- PRL-8-53, 1000mg czystej substancji ≥ 99%.
- Bromantan/Ladasten/Bromantane 1000mg, 99% zawartości Bromantanu w opak
- Mebicar / Mebicar / Temgicoluril – 30x cápsulas 100mg. Pureza ≥ 99%
Wybrane publikacje
Badania na zwierzętach i in vitro indeksowane w bazie PubMed; strona nie zawiera wskazówek dotyczących stosowania u ludzi.
- Gurbuz P Effects of noopept on ocular, pancreatic and renal histopathology in streptozotocin induced prepubertal diabetic rats 2023, Biotechnic & histochemistry : official publi. PMID 36946173
- Pelsman A GVS-111 prevents oxidative damage and apoptosis in normal and Down's syndrome human cortical neurons 2003, International journal of developmental neuro. PMID 12711349
- Kovalev GI [The role of non-NMDA glutamate receptors in the EEG effects of chronic administration of noopept GVS-111 in awake rats] 2002, Eksperimental'naia i klinicheskaia farmakolo. PMID 12596524
- Gudasheva TA The major metabolite of dipeptide piracetam analogue GVS-111 in rat brain and its similarity to endogenous neuropeptide cyclo-L-prolylglycine 1997, European journal of drug metabolism and phar. PMID 9358206
Kwalifikacja odczynnika. Materiału nie wolno stosować u ludzi. Zastosowanie weterynaryjne jest równie wykluczone. To produkt laboratoryjny wysokiej czystości wykorzystywany w badaniach HPLC i GC-MS. Nie stanowi leku, suplementu ani żywności.
