Phenylpyracetam
Cas No.: 77472-70-9
What is phenylpiracetam?
Phenylpiracetam, also referred to as phenylpiracetam, phenylpiracetam is a derivative of piracetam. It is formed as a result of the attachment of a phenyl group to piracetam. Other terms for this compound are phenotropil, carfedone, Fonturacetam, Carphedon and Phenotropil.
Like piracetam, its phenyl derivative is a compound with nootropic effects. Its effects are much stronger than those of the original compound, making it possible to use much smaller doses. The product is distinguished by almost 100% bioavailability, and the duration of action is about 3-5 hours.
Use of phenylpiracetam
As a nootropic preparation, the phenyl derivative of pyrrocetam is used to improve cognitive function, support memory and learning processes. It can be used to improve concentration. It is therefore applicable to learners, as well as those who work mentally. It can also be used for cognitive impairment and dementia in the elderly. It has a stimulating effect and increases motivation for action. It works well as a preparation for relieving depressive states. It can also improve motor coordination.
Mechanism of action
The compound penetrates the blood-brain barrier. Phenylpiracetam interacts with nicotinic receptors, thereby activating the cholinergic system. Another mechanism of action relates to dopamine reuptake inhibition. This increases the levels of this neurotransmitter and increases the number of receptors for dopamine. This translates into increased motivation and improved cognitive function. The product can increase the number of nerve connections in the hippocampus, in addition, it improves blood flow through the brain.
Phenylpiracetam – dosage
The recommended dose of phenylpiracetam is 100-200 mg, taken 3 times a day. Ad hoc use of the product is recommended. In order to enhance the nootropic effect, phenylpiracetam can be combined with the following supplements:
– choline
– Noopept
– rhodiola rosea
– Ashwagandha
– chinese citronella
– ginseng
– caffeine.
Since phenylpiracetam has a stimulant effect, it is not recommended to take it in the evening.
References:
- Malykh AG, Sadaie MR. Piracetam and piracetam-like drugs: from basic science to novel clinical applications to CNS disorders. Drugs. 2010 Feb 12;70(3):287-312; https://pubmed.ncbi.nlm.nih.gov/20166767/
- Zvejniece L et al. “Investigation into stereoselective pharmacological activity of phenotropil.” Basic Clin Pharmacol Toxicol. 2011 Nov;109(5):407-12; https://onlinelibrary.wiley.com/doi/full/10.1111/j.1742-7843.2011.00742.x
- Savchenko A., Zakharova N.S., Stepanov I.N., The phenotropil treatment of the consequences of brain organic lesions. Zh Nevrol Psikhiatr Im S S Korsakova., 2005; https://www.semanticscholar.org/paper/The-phenotropil-treatment-of-the-consequences-of-AIu-Ns/41aaf432d44ad0560300fbc547ad13b2a610f33b
- Bobkov G., et al, Pharmacological characteristics of a new phenyl analog of piracetam–4-phenylpiracetam. Biull Eksp Biol Med., 1983; https://pubmed.ncbi.nlm.nih.gov/6403074/
