Description
PRL 8-53
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Cas No. :51352-87-5
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Purity ≥ 99%
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Net weight: 1000mg
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Molecular Formula: C18H21NO2
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Molecular weight: 283.371 g-mol-1
What is PRL 8-53?
PRL 8-53 (3-[2-[benzylo(metylo)amino]ethyl]methyl benzoate) is a derivative of benzoic acid and phenylmethylamine. Other names for this compound are AC1L22UR, CTK4J4081, LS-36115, 3-(2-(benzylmethylamino)ethyl)benzoate hydrochloride
3-(2-benzylmethylaminoethyl) benzoic acid and ester hydrochloride
Methyl 3-(2-(methyl(phenylmethyl)amino)ethyl)methyl ester of benzoic acid. The compound was invented in the 1970s by an American scientist.
The compound affects the dopaminergic and cholinergic systems. It exhibits nootropic effects, that is, it improves cognitive function, enhances concentration and memory. High effectiveness is accompanied by the absence of significant side effects.
Application of PRL 8-53
The product can be used by people, they need to assimilate significant amounts of information, and there is a problem with memorization. Consequently, it helps improve short-term memory and working memory. The latter is responsible for the efficient storage and processing of information and accurate reasoning. In a similar way, m. In. Noopept.
PRL 8-53 can improve
cognitive functions
cognitive function, as shown in a human study. Volunteers were divided into a nootropic treatment group and a control group. Volunteers were instructed to remember 12 words, and such a memory test was conducted three times: immediately after ingestion of the product, the day after supplementation, and four days after supplementation. The results of the study were very promising – the group that used the tested nootropic preparation even showed a doubling of the score in the memory test.
The nootropic compound has shown beneficial effects in increasing motivation. It fosters the emergence of a desire for action and reduces procrastination, i.e. postponing responsibilities.
Mechanism of action
The product affects the cholinergic system by interacting with receptors for acetylcholine. Therefore, the compound improves the processes of transmission of nerve impulses. In contrast, the product’s effect on the dopaminergic system comes down to mimicking the action of dopamine. It binds to receptors for dopamine and stimulates their activity.
PRL 8-53 dosage
Based on the data provided in scientific studies, it is recommended to use the preparation at a dose of 0.05-1.2 mg/ kg body weight. Therefore, the preparation is usually used in a dose of 5 mg per day. Most importantly, it is not a product dedicated to daily, regular use. It is advisable to use the product occasionally, such as 2 to 3 times a week.
To increase the effect of the product on concentration, it is worth taking it together with choline. The combination with phosphatidylserine or Ginkgo biloba intensifies the beneficial effects of PRL 8-53 on memory. On the other hand, combining the product with caffeine allows to effectively increase energy levels.
Other chemical names:
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M-(2-(BENZYLMETHYLAMINO)ETHYL)BENZOIC ACID METHYL ESTER
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BENZOIC ACID, 3-(2-(METHYL(PHENYLMETHYL)AMINO)ETHYL)-, METHYL ESTER
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PRL-8-53 FREE BASE
References:
- Hansl, N.R. A novel spasmolytic and CNS active agent 3-(2-benzylmethylamino ethyl) benzoic acid methyl ester hydrochloride. Experientia 30, 271-272, 1974;
https://link.springer.com/article/10.1007/BF01934822
- Hansl NR, Mead BT. PRL-8-53: enhanced learning and subsequent retention in humans as a result of low oral doses of new psychotropic agent. Psychopharmacology (Berl), 1978;
https://europepmc.org/article/MED/418433
- Hansl NR, Hansl AB Learning and Memory Improvement through Chemistry: Dream or Reality in the Offing? Phi Delta Kappan, 1979;
