Description
The unit described here contains forskolin as a dry solid in a 1000 mg quantity. The questions below cover the entries that identify the material, the structural features that constrain how it is dissolved and stored, and the laboratory context in which such a diterpene is normally used. Zobacz również ten sam materiał w innej gramaturze: ¡CBD / Cannabidiol / Cannabidiol, Krishals ≥ 99,85.
What identifies forskolin unambiguously?
The registry number is 66575-29-9, the molecular formula C22H34O7 and the molar mass 410.50 g/mol. Those entries appear consistently across reagent suppliers and are the fields to cross-check against a delivery note. Names used in trade documents, including the botanical designations of its plant source, are not unique and should never replace the registry number.
Which compound class does it belong to?
Forskolin is a labdane-type diterpene isolated from Coleus forskohlii, a species also catalogued as Plectranthus barbatus. Its skeleton combines a bicyclic decalin framework with an oxygen bridge closing a further ring, and it carries several hydroxyl groups, an acetate ester and a terminal vinyl group. That combination of polar and non-polar regions is what makes the solubility behaviour of the material distinctive.
Why does the acetate group matter in handling?
An acetate ester is the most labile linkage in the molecule under aqueous conditions, particularly in alkaline media, where ester hydrolysis is a standard reaction. Keeping stock solutions neutral and free of adventitious base therefore protects the integrity of the material more than any temperature rule. Aqueous solutions left standing at high pH are the classic way to convert a well-characterised reagent into an undocumented mixture.
Which solvents are used for stock solutions?
The molecule is only sparingly compatible with water, and stock solutions are conventionally prepared in dimethyl sulfoxide or in ethanol. The chosen solvent then becomes part of the experimental record, because it is carried into every subsequent dilution. Small single-use aliquots are preferable to one large stock that is thawed repeatedly.
Where does the material appear in laboratory work?
Forskolin is a long-established tool reagent in cell-based assays, where it is used as an activator of adenylyl cyclase. That role explains why purity and correct identity matter more here than bulk quantity: the compound is applied at low concentrations against a measured baseline. A certificate stating the assay method behind the purity figure is therefore the document that carries the value of the unit. Zobacz również odczynnik laboratoryjny tej klasy: Löwenmähne / Igelsopran / Hericium Erinaceus < .
- Identity: CAS 66575-29-9, formula C22H34O7, molar mass 410.50 g/mol.
- Class: labdane diterpene from Coleus forskohlii, also listed as Plectranthus barbatus.
- Sensitive linkage: the acetate ester, especially under alkaline aqueous conditions.
- Solvents in routine use: dimethyl sulfoxide or ethanol, recorded with the stock concentration.
- Storage: sealed, dry, protected from light, with the lot certificate kept alongside.
Zobacz też w katalogu
- Löwenmähne / Igelsopran / Hericium Erinaceus < 10g 99% Soprano Pulv
- ¡CBD / Cannabidiol / Cannabidiol, Krishals ≥ 99,85% 1000mg!
- Lion's Mane / Hedgehog Soplum / Hericium Erinaceus < 10grams 99% po
- Azul de metileno / AZUL DE METILENO. Pureza ≥ 99,99% 1000mg.
Badania indeksowane w PubMed
Badania na zwierzętach i in vitro indeksowane w bazie PubMed; strona nie zawiera wskazówek dotyczących stosowania u ludzi.
- Salzillo A Forskolin affects proliferation, migration and Paclitaxel-mediated cytotoxicity in non-small-cell lung cancer cell lines via adenylyl cyclase/cAMP axis 2023, European journal of cell biology. PMID 36736051
- Jain A Adenylyl Cyclase Activator: Forskolin Mediates CREB ser133 Phosphorylation in the Hippocampus, Alleviates Autism-Like Deficits in a Valproic Acid Model of Wistar Rats 2025, Journal of neuroscience research. PMID 40457879
- Lee SY The Adenylyl Cyclase Activator Forskolin Increases Influenza Virus Propagation in MDCK Cells by Regulating ERK1/2 Activity 2023, Journal of microbiology and biotechnology. PMID 37644733
- Pinto C Activation and inhibition of adenylyl cyclase isoforms by forskolin analogs 2008, The Journal of pharmacology and experimental. PMID 18184830
Zakres stosowania. Preparat pozostaje poza zakresem użycia u ludzi. Poza użyciem u ludzi wyklucza się także użycie u zwierząt. To produkt laboratoryjny wysokiej czystości wykorzystywany w badaniach HPLC i GC-MS. Nie jest lekiem, wyrobem medycznym ani produktem spożywczym.
